Leaky gut, or intestinal permeability, occurs when the gut lining becomes irritated and the barrier between the gut and bloodstream becomes less selective.
This can contribute to immune activation, sensitivities, bloating and inflammation.
It is not a diagnosis — it’s a functional shift in the gut lining that can be rebuilt.
Why Intestinal Permeability Develops
Key contributors include:
chronic stress
dysbiosis
SIBO
yeast overgrowth
inflammatory foods or irritants
NSAIDs or long-term medication use
post-infectious changes
low stomach acid
hormone fluctuations
nutrient deficiencies (zinc, glutamine, omega-3s)
Permeability is almost always a response to something deeper.
Common Symptoms
Digestive symptoms:
bloating
gas
cramping
loose stools or diarrhoea
constipation
reflux
Whole-body symptoms:
headaches
joint pain
fatigue
skin issues
food sensitivities
histamine reactions
Symptoms often improve when the gut lining is soothed and the triggers are identified.
Links to Other Gut Patterns
Leaky gut commonly overlaps with:
dysbiosis
SIBO
histamine intolerance
food sensitivities
IBD (during flares)
chronic stress
Supporting the gut lining often reduces reactivity and improves tolerance.
Stress & the Gut Barrier
The gut lining is highly sensitive to stress hormones.
Fight-or-flight states can:
weaken the mucosal barrier
reduce blood flow to the gut
increase permeability
heighten sensitivity
This is often why symptoms fluctuate based on emotional load.
Testing Options
A stool test can reveal:
inflammation
zonulin (barrier marker)
secretory IgA
enzyme function
microbial patterns linked to permeability
Not everyone needs testing — many cases can be identified through symptoms.
Supporting Leaky Gut Long-Term
Effective support includes:
reducing irritation and inflammation
rebuilding mucosal integrity
balancing the microbiome
supporting digestive secretions
calming the gut–brain stress reflex
reintroducing foods safely
using targeted nutrition where helpful
The goal is stronger resilience, not endless restriction.
This Page in One Sentence
Leaky gut is a sign that the gut lining needs soothing and support — and it improves when inflammation, digestion, the microbiome and stress physiology are addressed together